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Genetic variants of G‐protein coupled receptors associated with pubertal disorders

BACKGROUND: The human hypothalamic–pituitary‐gonadal (HPG) axis is the regulatory center for pubertal development. This axis involves six G‐protein coupled receptors (GPCRs) encoded by KISS1R, TACR3, PROKR2, GNRHR, LHCGR, and FSHR. METHODS: Previous studies have identified several rare variants of t...

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Detalles Bibliográficos
Autores principales: Suzuki, Erina, Miyado, Mami, Kuroki, Yoko, Fukami, Maki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134480/
https://www.ncbi.nlm.nih.gov/pubmed/37122876
http://dx.doi.org/10.1002/rmb2.12515