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TRPM4 regulates hilar mossy cell loss in temporal lobe epilepsy

BACKGROUND: Mossy cells comprise a large fraction of excitatory neurons in the hippocampal dentate gyrus, and their loss is one of the major hallmarks of temporal lobe epilepsy (TLE). The vulnerability of mossy cells in TLE is well known in animal models as well as in patients; however, the mechanis...

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Detalles Bibliográficos
Autores principales: Mundrucz, Laura, Kecskés, Angéla, Henn-Mike, Nóra, Kóbor, Péter, Buzás, Péter, Vennekens, Rudi, Kecskés, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134545/
https://www.ncbi.nlm.nih.gov/pubmed/37101159
http://dx.doi.org/10.1186/s12915-023-01604-3