Gegen Qinlian standard decoction alleviated irinotecan-induced diarrhea via PI3K/AKT/NF-κB axis by network pharmacology prediction and experimental validation combination

BACKGROUND: The frequently occurred chemotherapy-induced diarrhea (CID) caused by irinotecan (CPT-11) administration has been the most representative side-effects of CPT-11, resulting in the chemotherapy suspension or failure. Our previous studies indicated that Gegen Qinlian formula exhibited a sig...

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Detalles Bibliográficos
Autores principales: Chen, Jiamei, Li, Min, Chen, Rong, Xu, Ziyi, Yang, Xiaoqin, Gu, Huan, Zhang, Lele, Fu, Chaomei, Zhang, Jinming, Wu, Yihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134581/
https://www.ncbi.nlm.nih.gov/pubmed/37106406
http://dx.doi.org/10.1186/s13020-023-00747-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134581/
https://www.ncbi.nlm.nih.gov/pubmed/37106406
http://dx.doi.org/10.1186/s13020-023-00747-3

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