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Deletion of DP148R, DP71L, and DP96R Attenuates African Swine Fever Virus, and the Mutant Strain Confers Complete Protection against Homologous Challenges in Pigs

The African swine fever virus (ASFV) has caused a devastating pandemic in domestic and wild swine, causing economic losses to the global swine industry. Recombinant live attenuated vaccines are an attractive option for ASFV treatment. However, safe and effective vaccines against ASFV are still scarc...

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Detalles Bibliográficos
Autores principales: Qi, Xiaolan, Feng, Tao, Ma, Zhao, Zheng, Linlin, Liu, Huanan, Shi, Zhengwang, Shen, Chaochao, Li, Pan, Wu, Panxue, Ru, Yi, Li, Dan, Zhu, Zixiang, Tian, Hong, Wu, Sen, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134827/
https://www.ncbi.nlm.nih.gov/pubmed/37017515
http://dx.doi.org/10.1128/jvi.00247-23