Release of High-Mobility Group Box-1 after a Raynaud’s Attack Leads to Fibroblast Activation and Interferon-γ Induced Protein-10 Production: Role in Systemic Sclerosis Pathogenesis

Raynaud’s Phenomenon (RP) leading to repetitive ischemia and reperfusion (IR) stress, is the first recognizable sign of systemic sclerosis (SSc) leading to increased oxidative stress. High-mobility group box-1 (HMGB1) is a nuclear factor released by apoptotic and necrotic cells after oxidative stres...

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Detalles Bibliográficos
Autores principales: Al-Adwi, Yehya, Atzeni, Isabella M., Doornbos-van der Meer, Berber, Abdulle, Amaal Eman, van Roon, Anniek M., Stel, Alja, van Goor, Harry, Smit, Andries J., Westra, Johanna, Mulder, Douwe J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134976/
https://www.ncbi.nlm.nih.gov/pubmed/37107169
http://dx.doi.org/10.3390/antiox12040794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134976/
https://www.ncbi.nlm.nih.gov/pubmed/37107169
http://dx.doi.org/10.3390/antiox12040794

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