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Release of High-Mobility Group Box-1 after a Raynaud’s Attack Leads to Fibroblast Activation and Interferon-γ Induced Protein-10 Production: Role in Systemic Sclerosis Pathogenesis
Raynaud’s Phenomenon (RP) leading to repetitive ischemia and reperfusion (IR) stress, is the first recognizable sign of systemic sclerosis (SSc) leading to increased oxidative stress. High-mobility group box-1 (HMGB1) is a nuclear factor released by apoptotic and necrotic cells after oxidative stres...
Autores principales: | Al-Adwi, Yehya, Atzeni, Isabella M., Doornbos-van der Meer, Berber, Abdulle, Amaal Eman, van Roon, Anniek M., Stel, Alja, van Goor, Harry, Smit, Andries J., Westra, Johanna, Mulder, Douwe J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134976/ https://www.ncbi.nlm.nih.gov/pubmed/37107169 http://dx.doi.org/10.3390/antiox12040794 |
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