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Should Airway Interstitial Fluid Be Used to Evaluate the Pharmacokinetics of Macrolide Antibiotics for Dose Regimen Determination in Respiratory Infection?

Macrolide antibiotics are important drugs to combat infections. The pharmacokinetics (PK) of these drugs are essential for the determination of their optimal dose regimens, which affect antimicrobial pharmacodynamics and treatment success. For most drugs, the measurement of their concentrations in p...

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Detalles Bibliográficos
Autores principales: Wang, Jianzhong, Zhou, Xueying, Elazab, Sara T., Park, Seung-Chun, Hsu, Walter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135031/
https://www.ncbi.nlm.nih.gov/pubmed/37107062
http://dx.doi.org/10.3390/antibiotics12040700