Sulfonamidoboronic Acids as “Cross-Class” Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii

Acinetobacter baumannii is a Gram-negative organism listed as an urgent threat pathogen by the World Health Organization (WHO). Carbapenem-resistant A. baumannii (CRAB), especially, present therapeutic challenges due to complex mechanisms of resistance to β-lactams. One of the most important mechani...

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Detalles Bibliográficos
Autores principales: Introvigne, Maria Luisa, Beardsley, Trevor J., Fernando, Micah C., Leonard, David A., Wallar, Bradley J., Rudin, Susan D., Taracila, Magdalena A., Rather, Philip N., Colquhoun, Jennifer M., Song, Shaina, Fini, Francesco, Hujer, Kristine M., Hujer, Andrea M., Prati, Fabio, Powers, Rachel A., Bonomo, Robert A., Caselli, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135033/
https://www.ncbi.nlm.nih.gov/pubmed/37107006
http://dx.doi.org/10.3390/antibiotics12040644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135033/
https://www.ncbi.nlm.nih.gov/pubmed/37107006
http://dx.doi.org/10.3390/antibiotics12040644

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