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Neutralizing Carbapenem Resistance by Co-Administering Meropenem with Novel β-Lactam-Metallo-β-Lactamase Inhibitors

Virulent Enterobacterale strains expressing serine and metallo-β-lactamases (MBL) genes have emerged responsible for conferring resistance to hard-to-treat infectious diseases. One strategy that exists is to develop β-lactamase inhibitors to counter this resistance. Currently, serine β-lactamase inh...

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Detalles Bibliográficos
Autores principales: Reddy, Nakita, Girdhari, Letisha, Shungube, Mbongeni, Gouws, Arnoldus C., Peters, Byron K., Rajbongshi, Kamal K., Baijnath, Sooraj, Mdanda, Sipho, Ntombela, Thandokuhle, Arumugam, Thilona, Bester, Linda A., Singh, Sanil D., Chuturgoon, Anil, Arvidsson, Per I., Maguire, Glenn E. M, Kruger, Hendrik G., Govender, Thavendran, Naicker, Tricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135050/
https://www.ncbi.nlm.nih.gov/pubmed/37106995
http://dx.doi.org/10.3390/antibiotics12040633