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Amyloid β-Peptide Effects on Glucose Regulation Are Dependent on Apolipoprotein E Genotype
The apolipoprotein E gene (APOE) confers the greatest genetic risk factor for Alzheimer’s disease (AD), wherein the ε4 allele confers an elevated risk compared with the ε3 allele. Biological mechanisms that differ across these alleles have been explored in mouse models wherein the murine Apoe gene h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135078/ https://www.ncbi.nlm.nih.gov/pubmed/37163733 http://dx.doi.org/10.1523/ENEURO.0376-22.2023 |