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Population Pharmacokinetic Study of Benzylpenicillin in Critically Unwell Adults

Pharmacokinetics are highly variable in critical illness, and suboptimal antibiotic exposure is associated with treatment failure. Benzylpenicillin is a commonly used beta-lactam antibiotic, and pharmacokinetic data of its use in critically ill adults are lacking. We performed a pharmacokinetic stud...

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Detalles Bibliográficos
Autores principales: Shah, Reya V., Kipper, Karin, Baker, Emma H., Barker, Charlotte I. S., Oldfield, Isobel, Philips, Barbara J., Johnston, Atholl, Lipman, Jeffrey, Rhodes, Andrew, Basarab, Marina, Sharland, Mike, Almahdi, Sarraa, Wake, Rachel M., Standing, Joseph F., Lonsdale, Dagan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135101/
https://www.ncbi.nlm.nih.gov/pubmed/37107004
http://dx.doi.org/10.3390/antibiotics12040643