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Population Pharmacokinetic Study of Benzylpenicillin in Critically Unwell Adults
Pharmacokinetics are highly variable in critical illness, and suboptimal antibiotic exposure is associated with treatment failure. Benzylpenicillin is a commonly used beta-lactam antibiotic, and pharmacokinetic data of its use in critically ill adults are lacking. We performed a pharmacokinetic stud...
Autores principales: | Shah, Reya V., Kipper, Karin, Baker, Emma H., Barker, Charlotte I. S., Oldfield, Isobel, Philips, Barbara J., Johnston, Atholl, Lipman, Jeffrey, Rhodes, Andrew, Basarab, Marina, Sharland, Mike, Almahdi, Sarraa, Wake, Rachel M., Standing, Joseph F., Lonsdale, Dagan O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135101/ https://www.ncbi.nlm.nih.gov/pubmed/37107004 http://dx.doi.org/10.3390/antibiotics12040643 |
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