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O-GlcNAcylation Is Required for the Survival of Cerebellar Purkinje Cells by Inhibiting ROS Generation

Purkinje cells (PCs), as a unique type of neurons output from the cerebellar cortex, are essential for the development and physiological function of the cerebellum. However, the intricate mechanisms underlying the maintenance of Purkinje cells are unclear. The O-GlcNAcylation (O-GlcNAc) of proteins...

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Detalles Bibliográficos
Autores principales: Liu, Fengjiao, Li, Shen, Zhao, Xin, Xue, Saisai, Li, Hao, Yang, Guochao, Li, Ying, Wu, Yan, Zhu, Lingling, Chen, Liping, Wu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135177/
https://www.ncbi.nlm.nih.gov/pubmed/37107182
http://dx.doi.org/10.3390/antiox12040806