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An Electrophysiological and Proteomic Analysis of the Effects of the Superoxide Dismutase Mimetic, MnTMPyP, on Synaptic Signalling Post-Ischemia in Isolated Rat Hippocampal Slices

Metabolic stress and the increased production of reactive oxygen species (ROS) are two main contributors to neuronal damage and synaptic plasticity in acute ischemic stroke. The superoxide scavenger MnTMPyP has been previously reported to have a neuroprotective effect in organotypic hippocampal slic...

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Detalles Bibliográficos
Autores principales: Puzio, Martina, Moreton, Niamh, Sullivan, Mairéad, Scaife, Caitriona, Glennon, Jeffrey C., O’Connor, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135248/
https://www.ncbi.nlm.nih.gov/pubmed/37107167
http://dx.doi.org/10.3390/antiox12040792