Fast and Sensitive Method for Simultaneous Quantification of Meropenem and Vaborbactam in Human Plasma Microsamples by Liquid Chromatography–Tandem Mass Spectrometry for Therapeutic Drug Monitoring

Meropenem (MRP)-Vaborbactam (VBR) is a novel beta-lactam/beta-lactamase inhibitor used for the management of difficult-to-treat Gram-negative infections. Among critically ill patients, MRP-VBR shows remarkable inter-individual variability in pharmacokinetic behavior, thus justifying the implementati...

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Detalles Bibliográficos
Autores principales: Barone, Rossella, Conti, Matteo, Giorgi, Beatrice, Gatti, Milo, Cojutti, Pier Giorgio, Viale, Pierluigi, Pea, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135283/
https://www.ncbi.nlm.nih.gov/pubmed/37107082
http://dx.doi.org/10.3390/antibiotics12040719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135283/
https://www.ncbi.nlm.nih.gov/pubmed/37107082
http://dx.doi.org/10.3390/antibiotics12040719

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