Novel Reversible Inhibitors of Xanthine Oxidase Targeting the Active Site of the Enzyme

Xanthine oxidase (XO) is a flavoprotein catalysing the oxidation of hypoxanthine to xanthine and then to uric acid, while simultaneously producing reactive oxygen species. Altered functions of XO may lead to severe pathological diseases, including gout-causing hyperuricemia and oxidative damage of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Rullo, Rosario, Cerchia, Carmen, Nasso, Rosarita, Romanelli, Virgilio, Vendittis, Emmanuele De, Masullo, Mariorosario, Lavecchia, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135315/
https://www.ncbi.nlm.nih.gov/pubmed/37107199
http://dx.doi.org/10.3390/antiox12040825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135315/
https://www.ncbi.nlm.nih.gov/pubmed/37107199
http://dx.doi.org/10.3390/antiox12040825

Ejemplares similares