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Predicting the Area under the Plasma Concentration-Time Curve (AUC) for First Dose Vancomycin Using First-Order Pharmacokinetic Equations

To treat critically ill patients, early achievement of the target area under the plasma concentration-time curve/minimum inhibitory concentration (AUC/MIC) in the first 24 h is recommended. However, accurately calculating the AUC before steady state is an obstacle to this goal. A first-order pharmac...

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Detalles Bibliográficos
Autores principales: Sujjavorakul, Kritsaporn, Katip, Wasan, Kerr, Stephen J., Wacharachaisurapol, Noppadol, Puthanakit, Thanyawee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135334/
https://www.ncbi.nlm.nih.gov/pubmed/37106993
http://dx.doi.org/10.3390/antibiotics12040630