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Construction of Curcumin and Paclitaxel Co-Loaded Lipid Nano Platform and Evaluation of Its Anti-Hepatoma Activity in vitro and Pharmacokinetics in vivo

PURPOSE: The present study aimed to construct a co-loading platform encapsulating curcumin and paclitaxel at ratios of 2:1–80:1 (w/w) designated “CU-PTX-LNP” and explored the synergistic effects of CU-PTX at different composite proportions on liver cancer cells using the combination index (CI) metho...

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Detalles Bibliográficos
Autores principales: Wei, Yuxun, Wei, Yumeng, Sheng, Lin, Ma, Jingwen, Su, Zhilian, Wen, Jie, Li, Lanmei, Jia, Qiang, Liu, Huiyang, Si, Hui, Xiong, Linjin, Chen, Jinglin, Cheng, Ju, Zuo, Ying, Yang, Hongru, Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135418/
https://www.ncbi.nlm.nih.gov/pubmed/37122500
http://dx.doi.org/10.2147/IJN.S399289