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Agomelatine, a Melatonin-Derived Drug, as a New Strategy for the Treatment of Colorectal Cancer

The potential use of agomelatine as an alternative treatment for colorectal cancer is evaluated in this work. The effect of agomelatine was studied in an in vitro model using two cell lines with different p53 statuses (HCT-116, wild-type p53, and HCT-116 p53 null) and an in vivo xenograft model. The...

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Detalles Bibliográficos
Autores principales: Moreno-SanJuan, Sara, Puentes-Pardo, Jose D., Casado, Jorge, Escudero-Feliu, Julia, Khaldy, Huda, Arnedo, Javier, Carazo, Ángel, León, Josefa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135458/
https://www.ncbi.nlm.nih.gov/pubmed/37107301
http://dx.doi.org/10.3390/antiox12040926