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Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation

Background: Why the adaptive immune system turns against citrullinated antigens in rheumatoid arthritis (RA) and whether anti-citrullinated protein antibodies (ACPAs) contribute to pathogenesis are questions that have triggered intense research, but still are not fully answered. Neutrophils may be c...

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Detalles Bibliográficos
Autores principales: Cîrciumaru, Alexandra, Afonso, Marcelo Gomes, Wähämaa, Heidi, Krishnamurthy, Akilan, Hansson, Monika, Mathsson-Alm, Linda, Keszei, Márton, Stålesen, Ragnhild, Ottosson, Lars, de Vries, Charlotte, Shelef, Miriam A., Malmström, Vivianne, Klareskog, Lars, Catrina, Anca I., Grönwall, Caroline, Hensvold, Aase, Réthi, Bence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135477/
https://www.ncbi.nlm.nih.gov/pubmed/37189377
http://dx.doi.org/10.3390/biom13040630