Enhanced Biosafety of the Sleeping Beauty Transposon System by Using mRNA as Source of Transposase to Efficiently and Stably Transfect Retinal Pigment Epithelial Cells

Neovascular age-related macular degeneration (nvAMD) is characterized by choroidal neovascularization (CNV), which leads to retinal pigment epithelial (RPE) cell and photoreceptor degeneration and blindness if untreated. Since blood vessel growth is mediated by endothelial cell growth factors, inclu...

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Detalles Bibliográficos
Autores principales: Harmening, Nina, Johnen, Sandra, Izsvák, Zsuzsanna, Ivics, Zoltan, Kropp, Martina, Bascuas, Thais, Walter, Peter, Kreis, Andreas, Pajic, Bojan, Thumann, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135490/
https://www.ncbi.nlm.nih.gov/pubmed/37189405
http://dx.doi.org/10.3390/biom13040658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135490/
https://www.ncbi.nlm.nih.gov/pubmed/37189405
http://dx.doi.org/10.3390/biom13040658

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