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Effects of GHR Deficiency and Juvenile Hypoglycemia on Immune Cells of a Porcine Model for Laron Syndrome

Laron syndrome (LS) is a rare genetic disorder characterized by low levels of insulin-like growth factor 1 (IGF1) and high levels of growth hormone (GH) due to mutations in the growth hormone receptor gene (GHR). A GHR-knockout (GHR-KO) pig was developed as a model for LS, which displays many of the...

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Detalles Bibliográficos
Autores principales: Schilloks, Marie-Christin, Giese, Isabella-Maria, Hinrichs, Arne, Korbonits, Lucia, Hauck, Stefanie M., Wolf, Eckhard, Deeg, Cornelia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135491/
https://www.ncbi.nlm.nih.gov/pubmed/37189345
http://dx.doi.org/10.3390/biom13040597