Cargando…

Regulatory Role of Insulin on Endogenous L1 ORF1 and NEFM Gene Expression through PI3K Signaling Pathway Specifically in Neuroblastoma Cell Line

BACKGROUND: One of the most important endogenous factors causing genomic instability in human cells is L1s retrotransposons. In this study, we assume that increased activity of L1 retrotransposons (specifically L1 expression) might be induced by hyperglycemia and hyperinsulinemia in neuroblastoma ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Sohrabi, Nasrin, Habibi, Laleh, Akrami, Seyed Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135514/
https://www.ncbi.nlm.nih.gov/pubmed/37124903
http://dx.doi.org/10.18502/ijph.v52i3.12146