Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities

Closely associated with aging and age-related disorders, cellular senescence (CS) is the inability of cells to proliferate due to accumulated unrepaired cellular damage and irreversible cell cycle arrest. Senescent cells are characterized by their senescence-associated secretory phenotype that overp...

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Detalles Bibliográficos
Autores principales: Silwal, Prashanta, Nguyen-Thai, Allison M., Mohammad, Haneef Ahamed, Wang, Yanshan, Robbins, Paul D., Lee, Joon Y., Vo, Nam V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135543/
https://www.ncbi.nlm.nih.gov/pubmed/37189433
http://dx.doi.org/10.3390/biom13040686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135543/
https://www.ncbi.nlm.nih.gov/pubmed/37189433
http://dx.doi.org/10.3390/biom13040686

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