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Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities
Closely associated with aging and age-related disorders, cellular senescence (CS) is the inability of cells to proliferate due to accumulated unrepaired cellular damage and irreversible cell cycle arrest. Senescent cells are characterized by their senescence-associated secretory phenotype that overp...
Autores principales: | Silwal, Prashanta, Nguyen-Thai, Allison M., Mohammad, Haneef Ahamed, Wang, Yanshan, Robbins, Paul D., Lee, Joon Y., Vo, Nam V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135543/ https://www.ncbi.nlm.nih.gov/pubmed/37189433 http://dx.doi.org/10.3390/biom13040686 |
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