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Epigallocatechin-3-Gallate Prevents the Acquisition of a Cancer Stem Cell Phenotype in Ovarian Cancer Tumorspheres through the Inhibition of Src/JAK/STAT3 Signaling

Three-dimensional tumorsphere cultures recapitulate the expression of several cancer stem cell (CSC) biomarkers and represent an effective in vitro platform to screen the anti-CSC properties of drugs. Whereas ovarian carcinoma is among the leading causes of death for women, ovarian CSC (OvCSC), a hi...

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Detalles Bibliográficos
Autores principales: Rodriguez Torres, Sahily, Gresseau, Loraine, Benhamida, Meriem, Fernandez-Marrero, Yuniel, Annabi, Borhane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135615/
https://www.ncbi.nlm.nih.gov/pubmed/37189618
http://dx.doi.org/10.3390/biomedicines11041000