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Regulatory Mechanisms and Reversal of CD8(+)T Cell Exhaustion: A Literature Review

SIMPLE SUMMARY: It has been known for decades that immune T cells, especially due to their capacity for powerful antigen-directed cytotoxicity, have become a central focus for engaging the immune system in the fight against cancer. Interest in harnessing T cells for cancer immunotherapy is rapidly g...

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Detalles Bibliográficos
Autores principales: Zhu, Wanwan, Li, Yiming, Han, Mingwei, Jiang, Jianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135681/
https://www.ncbi.nlm.nih.gov/pubmed/37106742
http://dx.doi.org/10.3390/biology12040541