Matrix Metalloproteinases Contribute to the Calcification Phenotype in Pseudoxanthoma Elasticum

Ectopic calcification and dysregulated extracellular matrix remodeling are prominent hallmarks of the complex heterogenous pathobiochemistry of pseudoxanthoma elasticum (PXE). The disease arises from mutations in ABCC6, an ATP-binding cassette transporter expressed predominantly in the liver. Neithe...

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Detalles Bibliográficos
Autores principales: Plümers, Ricarda, Lindenkamp, Christopher, Osterhage, Michel Robin, Knabbe, Cornelius, Hendig, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135689/
https://www.ncbi.nlm.nih.gov/pubmed/37189419
http://dx.doi.org/10.3390/biom13040672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135689/
https://www.ncbi.nlm.nih.gov/pubmed/37189419
http://dx.doi.org/10.3390/biom13040672

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