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Matrix Metalloproteinases Contribute to the Calcification Phenotype in Pseudoxanthoma Elasticum
Ectopic calcification and dysregulated extracellular matrix remodeling are prominent hallmarks of the complex heterogenous pathobiochemistry of pseudoxanthoma elasticum (PXE). The disease arises from mutations in ABCC6, an ATP-binding cassette transporter expressed predominantly in the liver. Neithe...
Autores principales: | Plümers, Ricarda, Lindenkamp, Christopher, Osterhage, Michel Robin, Knabbe, Cornelius, Hendig, Doris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135689/ https://www.ncbi.nlm.nih.gov/pubmed/37189419 http://dx.doi.org/10.3390/biom13040672 |
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