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Dimethyloxalylglycine Attenuates Steroid-Associated Endothelial Progenitor Cell Impairment and Osteonecrosis of the Femoral Head by Regulating the HIF-1α Signaling Pathway

Endothelial impairment and dysfunction are closely related to the pathogenesis of steroid-associated osteonecrosis of the femoral head (SONFH). Recent studies have showed that hypoxia inducible factor-1α (HIF-1α) plays a crucial role in endothelial homeostasis maintenance. Dimethyloxalylglycine (DMO...

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Detalles Bibliográficos
Autores principales: Shao, Wenkai, Li, Zilin, Wang, Bo, Gong, Song, Wang, Ping, Song, Beite, Chen, Zhixiang, Feng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135692/
https://www.ncbi.nlm.nih.gov/pubmed/37189610
http://dx.doi.org/10.3390/biomedicines11040992