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Development and Characterization of Inducible Astrocyte-Specific Aromatase Knockout Mice

SIMPLE SUMMARY: Recent work has shown that the steroid hormone17β-estradiol (E(2)) is also produced in the brain in both neurons and astrocytes. The current animal models for depleting E(2), specifically in astrocytes, are non-inducible, which can provide a developmental confound. It would be advant...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Pratap, Uday P., Lu, Yujiao, Sareddy, Gangadhara R., Tekmal, Rajeshwar R., Vadlamudi, Ratna K., Brann, Darrell W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135694/
https://www.ncbi.nlm.nih.gov/pubmed/37106821
http://dx.doi.org/10.3390/biology12040621