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Hybrid Multitask Learning Reveals Sequence Features Driving Specificity in the CRISPR/Cas9 System

CRISPR/Cas9 technology is capable of precisely editing genomes and is at the heart of various scientific and medical advances in recent times. The advances in biomedical research are hindered because of the inadvertent burden on the genome when genome editors are employed—the off-target effects. Alt...

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Detalles Bibliográficos
Autores principales: Vora, Dhvani Sandip, Yadav, Shashank, Sundar, Durai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135716/
https://www.ncbi.nlm.nih.gov/pubmed/37189388
http://dx.doi.org/10.3390/biom13040641