Inhibitory Peptide of Soluble Guanylyl Cyclase/Trx1 Interface Blunts the Dual Redox Signaling Functions of the Complex

Soluble guanylyl cyclase (GC1) and oxido-reductase thioredoxin (Trx1) form a complex that mediates two NO signaling pathways as a function of the redox state of cells. Under physiological conditions, reduced Trx1 (rTrx1) supports the canonical NO-GC1-cGMP pathway by protecting GC1 activity from thio...

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Detalles Bibliográficos
Autores principales: Cui, Chuanlong, Shu, Ping, Sadeghian, Tanaz, Younis, Waqas, Li, Hong, Beuve, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135718/
https://www.ncbi.nlm.nih.gov/pubmed/37107281
http://dx.doi.org/10.3390/antiox12040906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135718/
https://www.ncbi.nlm.nih.gov/pubmed/37107281
http://dx.doi.org/10.3390/antiox12040906

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