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Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model

The tauopathy of Alzheimer’s disease (AD) is first observed in the brainstem and entorhinal cortex, spreading trans-synaptically along specific pathways to other brain regions with recognizable patterns. Tau propagation occurs retrogradely and anterogradely (trans-synaptically) along a given pathway...

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Detalles Bibliográficos
Autores principales: Langer Horvat, Lea, Španić Popovački, Ena, Babić Leko, Mirjana, Zubčić, Klara, Horvat, Luka, Mustapić, Maja, Hof, Patrick R., Šimić, Goran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135744/
https://www.ncbi.nlm.nih.gov/pubmed/37189622
http://dx.doi.org/10.3390/biomedicines11041004