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Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model
The tauopathy of Alzheimer’s disease (AD) is first observed in the brainstem and entorhinal cortex, spreading trans-synaptically along specific pathways to other brain regions with recognizable patterns. Tau propagation occurs retrogradely and anterogradely (trans-synaptically) along a given pathway...
Autores principales: | Langer Horvat, Lea, Španić Popovački, Ena, Babić Leko, Mirjana, Zubčić, Klara, Horvat, Luka, Mustapić, Maja, Hof, Patrick R., Šimić, Goran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135744/ https://www.ncbi.nlm.nih.gov/pubmed/37189622 http://dx.doi.org/10.3390/biomedicines11041004 |
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