Engineering of a Bispecific Nanofitin with Immune Checkpoint Inhibitory Activity Conditioned by the Cross-Arm Binding to EGFR and PDL1

Re-education of the tumor microenvironment with immune checkpoint inhibitors (ICI) has provided the most significant advancement in cancer management, with impressive efficacy and durable response reported. However, low response rates and a high frequency of immune-related adverse events (irAEs) rem...

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Detalles Bibliográficos
Autores principales: Jacquot, Perrine, Muñoz-Garcia, Javier, Fleury, Maurine, Cochonneau, Denis, Gaussin, Rémi, Enouf, Elise, Roze, Caroline, Ollivier, Emilie, Cinier, Mathieu, Heymann, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135760/
https://www.ncbi.nlm.nih.gov/pubmed/37189383
http://dx.doi.org/10.3390/biom13040636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135760/
https://www.ncbi.nlm.nih.gov/pubmed/37189383
http://dx.doi.org/10.3390/biom13040636

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