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Force-Regulated Calcium Signaling of Lymphoid Cell RPMI 8226 Mediated by Integrin α(4)β(7)/MAdCAM-1 in Flow

MAdCAM-1 binds to integrin α(4)β(7), which mediates the rolling and arrest of circulating lymphocytes upon the vascular endothelia during lymphocytic homing. The calcium response by adhered lymphocytes is a critical event for lymphocyte activation and subsequent arrest and migration under flow. Howe...

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Detalles Bibliográficos
Autores principales: Sun, Dongshan, Luo, Zhiqing, Kong, Ying, Huang, Ruiting, Li, Quhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135767/
https://www.ncbi.nlm.nih.gov/pubmed/37189336
http://dx.doi.org/10.3390/biom13040587