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Force-Regulated Calcium Signaling of Lymphoid Cell RPMI 8226 Mediated by Integrin α(4)β(7)/MAdCAM-1 in Flow
MAdCAM-1 binds to integrin α(4)β(7), which mediates the rolling and arrest of circulating lymphocytes upon the vascular endothelia during lymphocytic homing. The calcium response by adhered lymphocytes is a critical event for lymphocyte activation and subsequent arrest and migration under flow. Howe...
Autores principales: | Sun, Dongshan, Luo, Zhiqing, Kong, Ying, Huang, Ruiting, Li, Quhuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135767/ https://www.ncbi.nlm.nih.gov/pubmed/37189336 http://dx.doi.org/10.3390/biom13040587 |
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