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Catecholaminergic and Cholinergic Systems Mediate Beneficial Effect of Vortioxetine on Diabetes-Induced Neuropathic Pain

The therapeutic potential of vortioxetine on mechanical hyperalgesia/allodynia was investigated in rats with streptozotocin-induced diabetes, and its possible mechanism of action was elucidated in this study. The obtained findings demonstrated that subacute vortioxetine treatment (5 and 10 mg/kg for...

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Detalles Bibliográficos
Autores principales: Turan Yücel, Nazlı, Kandemir, Ümmühan, Üçel, Umut İrfan, Demir Özkay, Ümide, Can, Özgür Devrim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135813/
https://www.ncbi.nlm.nih.gov/pubmed/37189755
http://dx.doi.org/10.3390/biomedicines11041137