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Pharmacologic Comparison of High-Dose Hesperetin and Quercetin on MDCK II Cell Viability, Tight Junction Integrity, and Cell Shape

The modulation of tight junction (TJ) integrity with small molecules is important for drug delivery. High-dose baicalin (BLI), baicalein (BLE), quercetin (QUE), and hesperetin (HST) have been shown to open TJs in Madin-Darby canine kidney (MDCK) II cells, but the mechanisms for HST and QUE remain un...

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Detalles Bibliográficos
Autores principales: Nakashima, Mio, Goda, Natsuko, Tenno, Takeshi, Kotake, Ayaka, Inotsume, Yuko, Amaya, Minako, Hiroaki, Hidekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135814/
https://www.ncbi.nlm.nih.gov/pubmed/37107328
http://dx.doi.org/10.3390/antiox12040952