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The Interplay between Intracellular Iron Homeostasis and Neuroinflammation in Neurodegenerative Diseases
Iron is essential for life. Many enzymes require iron for appropriate function. However, dysregulation of intracellular iron homeostasis produces excessive reactive oxygen species (ROS) via the Fenton reaction and causes devastating effects on cells, leading to ferroptosis, an iron-dependent cell de...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135822/ https://www.ncbi.nlm.nih.gov/pubmed/37107292 http://dx.doi.org/10.3390/antiox12040918 |