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Structural Basis of the Interaction between Human Axin2 and SIAH1 in the Wnt/β-Catenin Signaling Pathway

The scaffolding protein Axin is an important regulator of the Wnt signaling pathway, and its dysfunction is closely related to carcinogenesis. Axin could affect the assembly and dissociation of the β-catenin destruction complex. It can be regulated by phosphorylation, poly-ADP-ribosylation, and ubiq...

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Detalles Bibliográficos
Autores principales: Chen, Lianqi, Liu, Yan-Ping, Tian, Li-Fei, Li, Mingzhou, Yang, Shuyu, Wang, Song, Xu, Wenqing, Yan, Xiao-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135883/
https://www.ncbi.nlm.nih.gov/pubmed/37189394
http://dx.doi.org/10.3390/biom13040647