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Adenosine A(2A) Receptors Shut Down Adenosine A(1) Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation

Adenosine operates a modulation system fine-tuning the efficiency of synaptic transmission and plasticity through A(1) and A(2A) receptors (A(1)R, A(2A)R), respectively. Supramaximal activation of A(1)R can block hippocampal synaptic transmission, and the tonic engagement of A(1)R-mediated inhibitio...

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Detalles Bibliográficos
Autores principales: Lopes, Cátia R., Gonçalves, Francisco Q., Olaio, Simão, Tomé, Angelo R., Cunha, Rodrigo A., Lopes, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135888/
https://www.ncbi.nlm.nih.gov/pubmed/37189461
http://dx.doi.org/10.3390/biom13040715