Transcriptional Profiling of a Patient-Matched Cohort of Glioblastoma (IDH-Wildtype) for Therapeutic Target and Repurposing Drug Identification

Glioblastoma (GBM) is the most prevalent and aggressive adult brain tumor. Despite multi-modal therapies, GBM recurs, and patients have poor survival (~14 months). Resistance to therapy may originate from a subpopulation of tumor cells identified as glioma-stem cells (GSC), and new treatments are ur...

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Detalles Bibliográficos
Autores principales: Roddy, Aideen C., McInerney, Caitríona E., Flannery, Tom, Healy, Estelle G., Stewart, James P., Spence, Veronica J., Walsh, Jamie, Salto-Tellez, Manuel, McArt, Darragh G., Prise, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135924/
https://www.ncbi.nlm.nih.gov/pubmed/37189838
http://dx.doi.org/10.3390/biomedicines11041219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135924/
https://www.ncbi.nlm.nih.gov/pubmed/37189838
http://dx.doi.org/10.3390/biomedicines11041219

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