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Minimizing the Anticodon-Recognized Loop of Methanococcus jannaschii Tyrosyl-tRNA Synthetase to Improve the Efficiency of Incorporating Noncanonical Amino Acids

In the field of genetic code expansion (GCE), improvements in the efficiency of noncanonical amino acid (ncAA) incorporation have received continuous attention. By analyzing the reported gene sequences of giant virus species, we noticed some sequence differences at the tRNA binding interface. On the...

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Detalles Bibliográficos
Autores principales: Hu, Zhiyang, Liang, Jinming, Su, Taogeng, Zhang, Di, Li, Hao, Gao, Xiangdong, Yao, Wenbin, Song, Xiaoda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135938/
https://www.ncbi.nlm.nih.gov/pubmed/37189358
http://dx.doi.org/10.3390/biom13040610