One Scaffold, Two Conformations: The Ring-Flip of the Messenger InsP(8) Occurs under Cytosolic Conditions

Inositol poly- and pyrophosphates (InsPs and PP-InsPs) are central eukaryotic messengers. These very highly phosphorylated molecules can exist in two distinct conformations, a canonical one with five phosphoryl groups in equatorial positions, and a “flipped” conformation with five axial substituents...

Descripción completa

Detalles Bibliográficos
Autores principales: Kurz, Leonie, Schmieder, Peter, Veiga, Nicolás, Fiedler, Dorothea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135964/
https://www.ncbi.nlm.nih.gov/pubmed/37189392
http://dx.doi.org/10.3390/biom13040645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135964/
https://www.ncbi.nlm.nih.gov/pubmed/37189392
http://dx.doi.org/10.3390/biom13040645

Ejemplares similares