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One Scaffold, Two Conformations: The Ring-Flip of the Messenger InsP(8) Occurs under Cytosolic Conditions
Inositol poly- and pyrophosphates (InsPs and PP-InsPs) are central eukaryotic messengers. These very highly phosphorylated molecules can exist in two distinct conformations, a canonical one with five phosphoryl groups in equatorial positions, and a “flipped” conformation with five axial substituents...
Autores principales: | Kurz, Leonie, Schmieder, Peter, Veiga, Nicolás, Fiedler, Dorothea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135964/ https://www.ncbi.nlm.nih.gov/pubmed/37189392 http://dx.doi.org/10.3390/biom13040645 |
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