Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function

SIMPLE SUMMARY: Mitochondria are seriously fragmented, damaged and accompanied by insufficient productivity during heart failure. Studies have shown that PINK1 can mediate mitophagy to clear damaged mitochondria, activation of PGC-1a can promote mitochondrial regeneration, and Mfn2 can promote mitoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Zhuang, Liu, Zuheng, Li, Xudong, Zhang, Hao, Han, Dunzheng, Xiong, Wenjun, Zhou, Haobin, Yang, Xi, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135998/
https://www.ncbi.nlm.nih.gov/pubmed/37106782
http://dx.doi.org/10.3390/biology12040582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135998/
https://www.ncbi.nlm.nih.gov/pubmed/37106782
http://dx.doi.org/10.3390/biology12040582

Ejemplares similares