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Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function

SIMPLE SUMMARY: Mitochondria are seriously fragmented, damaged and accompanied by insufficient productivity during heart failure. Studies have shown that PINK1 can mediate mitophagy to clear damaged mitochondria, activation of PGC-1a can promote mitochondrial regeneration, and Mfn2 can promote mitoc...

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Detalles Bibliográficos
Autores principales:	Ma, Zhuang, Liu, Zuheng, Li, Xudong, Zhang, Hao, Han, Dunzheng, Xiong, Wenjun, Zhou, Haobin, Yang, Xi, Zeng, Qingchun, Ren, Hao, Xu, Dingli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135998/ https://www.ncbi.nlm.nih.gov/pubmed/37106782 http://dx.doi.org/10.3390/biology12040582

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