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Cellular Membrane Localization of Innate Immune Checkpoint Molecule CD47 Is Regulated by Radixin in Human Pancreatic Ductal Adenocarcinoma Cells

In the past decade, immune checkpoint inhibitors have exhibited potent antitumor efficacy against multiple solid malignancies but limited efficacy against pancreatic ductal adenocarcinoma (PDAC). Cluster of differentiation (CD) 47, a member of the immunoglobulin G superfamily, is overexpressed in th...

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Detalles Bibliográficos
Autores principales: Kobori, Takuro, Ito, Yui, Sawada, Yuka, Urashima, Yoko, Ito, Takuya, Obata, Tokio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136002/
https://www.ncbi.nlm.nih.gov/pubmed/37189735
http://dx.doi.org/10.3390/biomedicines11041117